Ashley M.
“I’ve been using the NAD+ Serum every morning and my skin feels noticeably smoother and more hydrated. It also layers really well under moisturizer.”
UNDEPLETED + NAD Renewal Serum · 30ml
Smoother-looking skin. Simple science. Three actives.
A lightweight daily serum made with NAD+, Copper Tripeptide-1 (GHK-Cu), and Hydrolyzed Collagen.
From $21 a bottle with the 5-pack
Choose your pack
- Free shipping
- 30-day returns, opened or not
- One-time purchase
UNDEPLETED + NAD Renewal Serum
Three ingredients people keep hearing about in skincare — explained simply, clearly, and without hiding them inside a mystery blend.
- Helps skin feel softer, smoother, and more hydrated
- Hydrates, so fine lines can look softer
- Leaves skin looking fresh and cared for
- Lightweight and fast-absorbing
- No sticky or greasy residue
- Made for face and neck
- For all skin types (patch test first if your skin is sensitive)
- Unisex
30ml · About 60 days of use · Morning + night
Choose your pack- 30-day returns, opened or not
- One-time purchase
Skincare without the nonsense.
Three actives, clearly named
NAD+, GHK-Cu, and hydrolyzed collagen, each named in full.A peptide with history
Scientists first found GHK in 1973. Skin researchers have studied it since the late 1980s. Not a trend.Fast routine
Face and neck in about 30 seconds.Lightweight
No thick cream. No greasy film.
What Is UNDEPLETED Made For?
For the things you actually notice in the mirror.
Skin can start to look dry, dull, rough, or less firm over time.
Fine lines can become easier to see. Your face may not look as fresh as it once did. Your neck and jawline can start showing changes too.
UNDEPLETED was made as a simple daily serum for the look and feel of your skin.
Use it for:
Fine LinesHydrates dry-looking texture, so fine lines can look softer. 
Smoother-Looking SkinHelps skin feel soft, hydrated, and smooth. 
The Look of FirmnessMade for skin that you want to look more firm, fresh, and cared for. 
Dry or Crepey-Looking TextureAdds lightweight moisture without a heavy cream or greasy finish. 
Face, Neck & JawlineOne serum for the areas people tend to notice most. 
Every Skin ToneOne simple formula made for all skin tones and for both men and women.
What’s inside
Three Actives. No Mystery.
We don’t chase more ingredients. We name our three key actives.
More actives don’t make better skincare. UNDEPLETED is built around three key actives, each named in full, each with one simple job.
NAD+
Nicotinamide Adenine DinucleotideA molecule found naturally in every living cell, where it helps with the everyday chemical reactions cells rely on. In skincare, it’s used as a skin-conditioning ingredient.It’s the ingredient this serum was built around — so we put its name on the bottle instead of hiding it in a blend.
Copper Tripeptide-1
Also called GHK-CuA tiny peptide: three amino acids — glycine, histidine, lysine — attached to copper. That’s the whole name. Scientists first identified it in the early 1970s, and it has been studied in skincare for decades.If we were going to use a peptide, we wanted one with decades behind it — and we wanted you to know exactly which one you’re getting.
Hydrolyzed Collagen
Collagen, broken into smaller piecesRegular collagen is too large to pass through skin, so this isn’t about “putting collagen back.” Hydrolyzed means it’s been broken into small fragments that sit near the surface and hold onto water.That’s what helps skin feel softer, smoother, and more hydrated — without a heavy or greasy finish.
Three ingredients. Three simple jobs. Nothing you can’t look up.
How to use
Simple Enough to Use Every Day
Three steps. About 30 seconds.
You don’t need a 10-step skincare routine.
Cleanse
Start with clean, dry skin.Use morning and night.
Apply
Place a few drops onto your face and neck.A little goes a long way.
Smooth
Gently spread or press the serum into your skin.Give it a moment to absorb.Then follow with your normal moisturizer.In the morning, finish with SPF.
A few drops. Face and neck. Morning and night. About 30 seconds. That’s the routine.
Sensitive Skin?
If your skin reacts easily to new products, patch test first.
Apply a small amount to your inner forearm and wait 24 hours before using it on your face.
For external use only. Avoid direct contact with the eyes. Stop use if irritation occurs.
Reviews
What people are saying.
Here’s what they had to say about this formula.
What Reviewers Talked About Most
Across these 15 reviews:
10 of 15mention the texture, absorption, or how the serum feels.
7 of 15mention how simple it is to add to their routine.
3 of 15mention that it does not feel sticky, greasy, or heavily fragranced.
Daniel R.
“I wanted something simple I could add to my routine without five extra steps. This serum absorbs fast and doesn’t leave my skin feeling sticky.”
Samantha K.
“[…] my skin just looked healthier and more refreshed. It’s become one of those products I actually look forward to using.”
Michael T.
“I’m not normally a skincare person, but this was easy enough to stick with. A few drops in the morning and I’m done.”
Jessica L.
“The texture is probably my favorite part. It feels lightweight, clean, and leaves my skin feeling really soft.”
Chris B.
“I bought it because I kept hearing about NAD+. I like that this gives me an easy way to incorporate it into my skincare routine.”
Nicole A.
“My skin tends to look tired in the morning, and this has become my go-to before work. My face feels more hydrated and refreshed.”
Ryan C.
“No complicated routine. No heavy fragrance. It absorbs quickly and feels good on my skin.”
Lauren P.
“I’ve tried a lot of serums that feel greasy or heavy. This one disappears into my skin almost immediately.”
Kevin S.
“I’ve been using it consistently […]. My skin feels smoother, and I like how simple the product is.”
Emily J.
“This is the kind of serum that makes your routine feel a little more premium without making it complicated.”
Marcus H.
“I started using it at night after washing my face. It’s lightweight, comfortable, and my skin feels great in the morning.”
Rachel D.
“I originally bought it because the NAD+ concept caught my attention, but I kept using it because I genuinely like how it feels on my skin.”
Brandon W.
“Probably one of the easiest skincare products I’ve added to my routine. A few drops, rub it in, and you’re good.”
Megan F.
“My skin feels softer and more hydrated since I started using it. The packaging also looks really nice sitting on my bathroom counter.”
Our guarantee
30 days. Opened or not.
Try it for a month. If it isn’t for you, send it back within 30 days of delivery for a refund, even if you’ve used it.
What to expect
- From your first drop
- Light and water-like. It absorbs fast, with no sticky or greasy feel.
- With regular use
- Skin that feels hydrated, soft, and smooth. How much your skin’s look changes, and how fast, varies from person to person.
That’s why you get 30 days, opened or not.
Returns
& Refunds
Policy
& Refunds
Policy
To start a return, email us with your order number. We refund the product price, and original shipping too if we made a mistake or it arrived damaged or wrong. Full details are in our Returns & Refunds Policy.
Choose Your Pack
One bottle lasts about two months.
One-time purchase. No subscription. No automatic refill. Nothing to cancel.
- Free shipping
- 30-day returns, opened or not
- Secure checkout
The story behind the name
Why UNDEPLETED?
What does it mean to feel UNDEPLETED?
To be undepleted is to move through life without constantly running yourself empty.
It’s taking care of what you have before it feels worn down.
Your skin. Your energy. Your time. Your sense of self.
It’s choosing simple rituals that help you feel restored, composed, and ready for what comes next.
For your skin, that means hydration, softness, and a fresh, healthy-looking appearance — without turning skincare into another thing you have to manage.
UNDEPLETED is more than the name of a serum.
It’s a way of taking care of yourself without overcomplicating it.
Stay full. Stay fresh. Stay UNDEPLETED.
UNDEPLETED + NADThe serum in use
Questions
Frequently Asked Questions
Is this a subscription?
No.
Every order is a one-time purchase.
There is no membership, auto-refill, or recurring charge.
How long does one bottle last?
One 30ml bottle lasts approximately 60 days when used twice daily as directed.
How long yours lasts can vary depending on how much you use each time.
How long does shipping take?
Shipping is free on every order.
We email you a tracking link once your order ships.
What if I want to return it?
You can return any order within 30 days of delivery, opened or not. Even if you’ve used it.
To start a return, email us with your order number. We refund the product price, and original shipping too if we made a mistake or it arrived damaged or wrong.
If anything arrives damaged, wrong, or missing, we’ll replace it or refund it in full.
Full details are in our Returns & Refunds Policy.
What exactly is UNDEPLETED?
UNDEPLETED + NAD Renewal Serum is a lightweight topical serum for your face and neck.
It contains NAD+, Copper Tripeptide-1 (GHK-Cu), and Hydrolyzed Collagen.
It is made to help skin feel hydrated, soft, and smooth, and look fresh and cared for.
It is a cosmetic product, not a medicine.
How do I use it?
Use it morning and night on clean, dry skin.
Apply a few drops to your face and neck and gently smooth it in.
Let it absorb before applying your moisturizer.
During the day, finish your routine with SPF.
Can I use it if I have sensitive skin?
The formula is intended for all skin types.
Any skincare product can irritate some people.
If your skin is sensitive or reactive, patch test first.
Can I use it with my other skincare products?
Yes.
Because UNDEPLETED is a lightweight serum, it can be used before heavier products like moisturizer.
In the morning, apply SPF as the last step in your skincare routine.
If you use strong acids, retinoids, or other products that tend to irritate your skin, introduce new products slowly.
What is NAD+?
NAD+ stands for Nicotinamide Adenine Dinucleotide.
It’s a molecule naturally found in living cells and helps with many normal chemical reactions inside the body.
In this serum, NAD+ is used as a cosmetic skin-conditioning ingredient.
What is GHK-Cu?
GHK-Cu is also called Copper Tripeptide-1.
It is a tiny peptide made from three amino acids attached to copper.
Scientists first identified GHK in human blood plasma in the early 1970s, and it has been studied in cosmetic science for decades.
What is Hydrolyzed Collagen?
Hydrolyzed collagen is collagen that has been broken into smaller pieces.
When used on the skin, those fragments help hold water near the surface.
That can help skin feel softer, smoother, and more hydrated.
It does not replace the collagen already inside your skin.
Is it for men or women?
Both.
Skin is skin.
There is no separate men’s version or women’s version.
How long does it keep?
The product information provided for the serum lists a shelf life of up to 3 years unopened and approximately 24 months after opening when stored properly.
How do I contact someone?
Email us at support@undepletedsup.com, or use the Contact page.